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UBQLN2/ubiquilin 2 mutation and pathology in familial amyotrophic lateral sclerosis

(Source 1) However, research shows that in cases of dysbiosis (microbiome imbalances) and endotoxemia, a higher intake of vitamin C helps to restore gut-liver functions

The release rate of doxorubicin can be increased by using nanocarriers prepared by crosslinking bromelain with an ortho-ester-based crosslink agent

In this context, the anti-inflammatory properties of PYC, particularly its inhibition of the TLR4NF-B signaling pathway, represent a critical link between redox regulation and immune modulation ( Recent translational preclinical studies have explored the use of PYC-based nanocomposites as a strategy to enhance the delivery of antiviral agents, including molnupiravir, for the treatment of COVID-19 ( Overall, PYCs antiviral effects are likely mediated by a combination of direct viral inhibition and host-directed mechanisms, including modulation of oxidative stress and immune responses