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Interaction energies were calculated for predicting docking positions and selecting the binding pose that had the lowest binding energy (kcal mol 1 )

The FDA has also recommended that the healthcare professionals avoid prescribing and dispensing products containing more than 325 mg of APAP per dose [7]

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The peptide is unique among neuropeptides in several respects: it does not conform to typical neuropeptide structural motifs, its distribution in the brain and periphery differs from classical sleep-promoting substances, and it appears to exert effects through multiple pathways rather than through a single characterized receptor system