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Four Phase IV clinical trials of the vaccine are ongoing (EUCTR2021-002327-38-NL, NCT05030974, NCT05037266, and NCT05075538) ( Alter et al

Futhermore, in HepG2 cells, GA treatment activated AMPK signaling and reduced mRNA expression of key transcription factors in fatty acid synthesis, including SREBP-1c, LXR, and ACC, as well as fatty acid transporter proteins such as CD36 and FATP2, which mitigated palmitic acid-induced lipid accumulation (Tanaka et al., 2020a)