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These alterations trigger inflammatory cascades through the TLR4/NF-B pathway, while abnormally elevated systemic inflammation indices (NLR, PLR) reflect chronic inflammatory status

Though avocado consumptions benefits have been studied in older adults and children, no randomized controlled trials had studied its cognitive effects on adults with overweight or obesity, despite 70% of the American adult population falling into that category, said graduate student Caitlyn Edwards, the first author of the study

Although a mouse model clearly does not directly translate to humans, this elegant study provides support for the theory that the abnormal gastrointestinal function so commonly seen in children with autism [23] may contribute to or even cause some of the symptoms

Zhuo L, et al