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The imine was then evaluated for mouse plasma stability and found to be rapidly hydrolyzed, due to an isopropyl ester present in this compound (T 1/2 120 min in plasma and in liver microsomes (EC50350 nM)

[34] Macrophages are responsible for producing the cytokines involved in cytokine storm syndrome (CSS), which refers to the cascade of cytokine production resulting from an unregulated host immune response to different stimuli

Siyuan Song, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, it is very important to note that their concentrations are highly increased by our lifestyle and environmental factors such as UV radiation, pollution, smoking and poor diet