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Cell-to-cell communication in the brain relies upon a surprising array of molecules, from gaseous molecules (e.g., nitric oxide) to classical transmitters (e.g., glutamate), as well as unexpected molecules (e.g., d-serine), and a range of peptides

In addition, dsDNA-induced cGAS-STING signaling has been shown to promote the development of arthritis through the induction of inflammatory factors in FLSs, accompanied by enhanced migration and invasion (63, 65)

Neuronal cancer cells release neurotrophic factors and cytokines, that can activate non-neuronal cancer cells leading to their proliferation (96)

On the other hand, U251MG (p53mt) displayed a high sensitivity upon cisplatin treatment, indicated either by low cellular viability or high amounts of apoptotic cells (Figures 1a and b)