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(1) Loren Pickart and Anna Margolina (2018) Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data International Journal of Molecular Sciences, 2018 Jul 7, Volume 19 (Issue 7), Page 1987

In summary the researchers involved in these studies have explained it this way, IGF-1 as well as activated calcineurin, induces expression of the transcription factor GATA-2, which accumulates in a subset of myocyte nuclei, where it associates with calcineurin and a specific dephosphorylated isoform of the transcription factor nuclear factor of activated T cells or NF-ATc1. Thus, IGF-1 induces calcineurin-mediated signaling and activation of GATA-2, a marker of skeletal muscle hypertrophy, which cooperates with selected NF-ATc isoforms to activate gene expression programs leading to increased contractile protein synthesis and muscle hypertrophy

Compound Type: Peptide research material Form: Lyophilized powder Purity: 98% (HPLC verified) Handling: Intended for controlled laboratory environments only Storage: Refrigerated or frozen according to research standards For laboratory research use only

Only 78 (16%) of patients were previously aware of their diagnosis of HH (Table 1)