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The TNF- treatment of human keratinocytes increased the expression of 26 genes involved in inflammatory pathways, including chemokines like CXCL8 and CXCL10

& Bucciantini, M

A recombinant form of human G-CSF, specifically the recombinant methionyl human G-CSF NEUPOGEN (filgrastim), was initially approved with an indicated use to decrease the incidence of infection and reduce severe neutropenia

Here are some of the drugs shown to affect melatonin: Antidepressants including Fluoxetine (Prozac), Paroxetine (Paxil), Sertraline (Zoloft), Citalopram (Celexa), Escitalopram (Lexapro), Venlafaxine (Effexor) Benzodiazepines including Diazepam (Valium), clorazepate (Tranxene), lorazepam (Ativan), Clonazepam (Klonopin), Alprazolam (Xanax) Antipsychotics including Aripiprazole (Abilify), Quetiapine (Seroquel), Risperidone (Risperdal), Olanzapine (Zyrexa), Haloperidol (Haldol), Paliperidone (Invega), Ziprasidone (Geodon) If you take one of these drugs, you should consider supplementing with melatonin every night