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Description

Berlin: Duncker and Humblot Green, Philip 1993

High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner

Particular branch structures of the N -glycan, Man 7 GlcNAc 2 , Man 6 GlcNAc 2 , and Man 5 GlcNAc 2 , all of which expose a terminal 1,6-linked mannosyl residue and prevent reglycosylation, become signals for degradation via ERAD, directing a misfolded protein from pro-folding to pro-degradation