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The major findings are that aerobic glycolysis is not a symptom of impaired mitochondrial function, and that glutamine supports mitochondrial oxidative metabolism when pyruvate derived from glucose is converted into lactate and secreted 2,3,4

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Trends in the incidence and DALYs of schizophrenia at the global, regional and national levels: Results from the Global Burden of Disease Study 2017

10.2.4 Combination with coordinated undermining of survival paths DSF with aprepitant, auranofin, captopril, celecoxib, itraconazole, minocycline, quetiapine, and sertraline constituted a CUSP9 regimen that was used in combination with TMZ to synergistically disrupt the active survival pathway in GBM, block multiple signaling pathways, and make GBM vulnerable to the cytotoxic effects of TMZ (Skaga et al., 2019)