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People taking MAO inhibitors cannot take bupropion at all, which means the combination with tirzepatide is irrelevant for this group

Cell Death Dis (2017) 8(3):e2716

It often occurs after a meal or when you lie down, and it can feel like burning in your throat or a pain in your chest, says Sonja Olsen, M.D., a gastroenterologist with Tampa General Hospitals Gastro Group of the Palm Beaches