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Regarding safety, a recent literature review of double-blinded RCTs examined the safety and toxicity profiles of turmeric and curcumin in medical applications (237)

PloS One (2020) 15:e0240729

Still, it influences the release of TGF-1, the activation and proliferation of fibroblasts, and their differentiation into myofibroblasts, mostly mediated by the RANKL/NF-B pathway

The SARS-CoV-2 viral N protein has been found to increase the synthesis of IL-6, which has been linked to the downregulation of glutamate cysteine ligase (GCL), the rate-limiting enzyme in GSH synthesis [12,13]