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By no longer specifying a claim for E/M services as the default attribution basis in the sixth criterion, and instead making the default attribution based on covered professional services, we had aimed to eliminate the need to create unique attribution bases that are tied to a specific Advanced APM's attribution methodology

Nature 475, 231-234

While DNA methylation may be age, gender, and cell-type specific, MTHFR polymorphism might not be always associated with hypomethylation of DNA

7.4 Translational research (bridging basic science and clinical applications) To bridge the gap between research and medicine is a major challenge, but could be an opportunity if turned into clinically actionable knowledge