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For example: Fatigue, unexplained weight loss, or abdominal pain may indicate liver disease or cancer Easy bruising, night sweats, or feeling full quickly (early satiety) may suggest a myeloproliferative disorder Swelling in the legs, reduced urine output, or persistent nausea may point to kidney disease In cases of very high B12 from injections (not oral supplements), some people have reported headache, nausea, diarrhea, facial flushing, or skin rash

Yes, and this is one of the most common reasons oral supplements stop working for people

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Vitamin IV infusions are a safe and effective way to get all the essential vitamins, amino acids and minerals that your body needs through an intravenous drip immediately into your bloodstream