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Existing findings are largely derived from preclinical and exploratory models, and the mechanistic scope of these observations remains under ongoing investigation

Oliver RTD, Mead GM, Rustin GJS, Joffe JK, Aass N, Coleman R, Gabe R, Pollock P, Stenning SP (2011) Randomized trial of carboplatin versus radiotherapy for stage I seminoma: mature results on relapse and contralateral testis cancer rates in MRC TE19/EORTC 30982 study (ISRCTN27163214)

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For example, there is no broadly available tool to analyze diversity of all trials resulting in FDA approval via a publicly available database (requiring manual collection and analysis of FDA Snapshot data, which makes any ongoing analysis more challenging)