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Mixing can cause degradation or altered bioavailability

doi: 10.1186/s12974-017-0935-1 15 ElefanteC.BrancatiG

300 During hypoxia, mTORC1 promotes HIF-1 expression by directly phosphorylating signal transducer and activating transcription 3 (STAT3) to stimulate HIF-1 mRNA transcription 301 (Fig

Nucleic Acids Res 53:D1162D1172 Liang X, Hu M, Rogers CQ, Shen Z, You M (2011) Role of SIRT1-FoxO1 signaling in dietary saturated fat-dependent upregulation of liver adiponectin receptor 2 in ethanol-administered mice