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ICIs antagonize immune checkpoint molecules (e.g., PD-1/PD-L1, cytotoxic T lymphocyte antigen-4 [CTLA-4]) to disinhibit cytotoxic T cell activity, reinvigorating antitumor immunity (93)

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Cold Spring Harb Perspect Biol 7(10):a020545 Shabana MB, Ibrahim HM, Khadre SEM, Elemam MG (2012) Influence of rifampicin and tetracycline administration on some biochemical and histological parameters in albino rats