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doi: 10.1002/1873-3468.12702 41 JeonJYNamJYKimHAParkYBBaeSCSuhCH

In contrast, after EGCG treatment, the MDA levels in myocardial tissue decreased, and SOD activity increased

In rodents, activation of AMPA receptors by the KET metabolite (2R,6R)-hydroxynorketamine has initially been thought essential to replicate KET antidepressant effects while administration of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione (NBQX), an AMPA receptor antagonist, blocks KET effects (Zanos et al., 2016)

MASH patients also accumulate microtubule-associated protein 1A/1B-light chain 3 (LC3-II) and sequestosome-1 (p62), a marker of Mallory-Denk bodies, which are associated with disease complications [104]