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Li et al., 2017), which can contribute to the accumulation of senescent cells in tissues

6 Challenges and solutions of anti-angiogenic targeted therapy for GC Anti-angiogenic drugs target various aspects of tumor angiogenesis to block the formation of blood vessels to cut off the nutrient and supply to tumor cells, resulting in a hypoxic microenvironment (164)

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This suggests that Ca 2+ may more specifically inhibit OsGR activity and deplete GSH production than the other ions Mg 2+ , K + , and Na + in rice cells