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Declining testosterone levels might even induce hypogonadism [150], thus creating a feedback-loop that further exacerbates these conditions

Mice model carrying a selective ablation of AR in myofibers (AR skm/y mice) exhibits a decrease of glucose uptake and glycolytic activity, thus contributing to early-onset type 2 diabetes

Mitochondrial dysfunction, manifested in the abnormal activities of the electron transport chain and impaired energy metabolism, greatly contributes to ASD