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Proc Natl Acad Sci U S A 91:12614, PMID: 8108398 Kuchino Y, Mori F, Kasai H, Inoue H, Iwai S, Miura K, Ohtsuka E, Nishimura S (1987) Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

Bigger results are possible in skin that still has an intact fiber network that can tighten up, as opposed to just being able to grow new collagen in skin thats severely lax