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Okuda et al., 2001)

Under hypoxic conditions, PHD enzymes are inactivated, stabilizing HIF-1 and HIF-2, which then translocate to the nucleus

More recently, an open-label pilot has found tapering from a high dose of the long-acting lisdexamfetamine, a precursor of dextroamphetamine, to be feasible and well-tolerated [45]