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For example, PD-L1Pep-2 peptide-labeled doxorubicin-loaded liposomes increased the CD8 + T-cell/regulatory T-cell ratio in mouse colon tumor tissues more efficiently than combined treatment with PD-L1Pep-2 peptide and untargeted doxorubicin-loaded liposomes 101

In adults, BMP9 is synthesized in the liver by hepatic stellate cells, while BMP10 is primarily synthesized in the right atrium, with lower expression also detected in the liver 25

Wang L, Jiang Y, Yaseen A, Li F, Chen B, Shen XF, Zheng C, Zhang GL, Wang MK (2021) Steroidal alkaloids from the bulbs of Fritillaria pallidiflora Schrenk and their anti-inflammatory activity

T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies