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The other two common reasons for sweating are stress and eating spicy foods

Nevertheless, several formidable challenges persist in translating this paradigmatic understanding into clinically validated therapeutic interventions

Vomiting is often bilious (1) and associated to other gastrointestinal symptoms, such as abdominal pain, which is described in up to 80% of children, retching, anorexia, disabling nausea and diarrhea (68)

Therefore, cerebral serotonin is synthetized in the brain, where it plays a major role in mood regulation and, after transformation in melatonin, in sleep regulation (155, 156), as summarized in Figure 1