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Patients infected with HP give high readings of the isotope because of the breakdown of urea to CO2 (and ammonia) through the action of HP urease [14]

Other destructive approaches include focused ultrasound [65] , CO 2 laser, radiofrequency ablation [66] , photodynamic therapy [67,68] , Er:YAG or Nd:YAG laser [69] , and electrodessication [70]

High doses are required for oral B12 because it must be broken down in the digestive tract, which involves both intrinsic factor and passive diffusion