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Substrate titration and time-course experiments showed that 12 h of labeling with 250500 M BP or BMP substrate provides an optimal signal-to-noise ratio (Supplementary Fig

J Clust Sci 30:15911597

These specialized proteins and immune cells then work in conjunction to form an immunological memory streamlining the immune response and preventing disease in the future by remembering what specific invading pathogens look like

The experimental mouse models of autoimmune encephalomyelitis (EAE) and cuprizone (a copper-chelator causing demyelination) are the most commonly employed animal models used to study different aspects of MS pathology