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Because of the increased risk, today all vegan associations encourage vegans to take B12 in the form of fortified products, supplements or algae

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Ibuprofen, an OAT3 inhibitor inhibited the uptake of pemetrexed in OAT3-expressing cell cultures with an average [I u]/IC 50 ratio of 0.38

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doi: 10.1074/mcp.TIR120.002048 88 KimHJKimTHoffmanNJXiaoDJamesDEHumphreySJet al

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The study and its protocol were conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of Istituto Superiore di Sanit (protocol code PRE-726/16 on 20 August 2016)

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