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Isotope tracing experiments Uniformly labelled glucose ( 13 C 6 -glucose) was used at equimolar amounts as found in experimental medium (5.56 mM) and both 13 C 6 -glucose and 500 M hydrogen peroxide were spiked into the medium at time point 0 and metabolites were extracted after 15 min (Fig

Unlike native collagen, which is poorly absorbed, CPs are thought to stimulate endogenous collagen synthesis and modulate extracellular matrix metabolism, thereby improving skin hydration, elasticity, and overall appearance [6]