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In rodent studies, animals with greater GLUT4 expression display heightened insulin sensitivity, whereas those with reduced GLUT4 levels demonstrate impaired insulin signaling

This study was conducted according to the principles of the Declaration of Helsinki, and was approved by the Medical Ethics Committee of Tokyo Womens Medical University (No.3818)

Additionally, the gut microbiota regulates the accumulation of Th17 cells in the lungs by affecting the expression of RegIII (an IL-22-induced antibacterial protein specific to Gram-positive bacteria) and IL-22, thus impacting the immune response during fungal infection (63)

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