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Stem cell factor/mast cell/CCL2/monocyte/macrophage axis promotes Coxsackievirus B3 myocarditis and cardiac fibrosis by increasing Ly6C(high) monocyte influx and fibrogenic mediators production

doi: 10.1016/j.exer.2025.110656 171 YangZYanYWangLZouGLuL

As a result, patients may feel the benefits sooner

SAM differentially regulates MAT isoforms: it sustains MAT1A expression but suppresses MAT2A, creating a negative feedback loop that limits excessive MAT2A-driven SAM production (181)