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The processed data matrix was exported as a.csv file and analyzed using Metaboanalyst 6.0v( Statistical analysis Clinical severity was assessed using CARS scores obtained at baseline and after completion of the three-month GF-MKD intervention

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Consequently, the lower proportional reporting for belimumab may be attributable to a channeling bias, where the pronounced infection risk in the SLE population is so overwhelmingly driven by the background disease severity and concomitant medications that the specific contribution of belimumab becomes more difficult to detect in a spontaneous reporting system