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The latter is commonly defined as a spontaneous, programmed cell death finely determined by effector molecules and strictly regulated by signaling pathways, which can be further divided into apoptosis (1972), lysosomal cell death (2000), pyroptosis (2001), netotic cell death (2004), necroptosis (2005), immunogenic cell death (2005), entotic cell death (2007), parthanatos (2009), ferroptosis (2012), autophagic cell death (2013), alkaliptosis (2018), and oxeiptosis (2018) [70]

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Patients who have previously had laser hair removal and developed hyperpigmentation may not be suitable candidates