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An enzyme-engineered nonporous copper(I) coordination polymer nanoplatform for cuproptosis-based synergistic cancer therapy

Although there still lasks data showing a direct benefitial effect of vitamin E in COVID-19 patient, recent meta-analyses and narrative reviews have suggested that vitamin E supplementation, or a vitamin-E-rich diet such as the Mediterranean diet, significantly lowers HbA1c, fasting insulin, and HOMA-IR in patients with T2DM (64, 65)

J Pineal Res 66(4):e12564 Wolden-Hanson T, Mitton DR, McCants RL, Yellon SM, Wilkinson CW, Matsumoto AM, Rasmussen DD (2000) Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat

5-amino-1-methylquinolinium (5-amino-1MQ) represents a significant advancement in the field of metabolic research, emerging as a potent, selective inhibitor of nicotinamide N-methyltransferase (NNMT)