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FIGURE 1 4 NLRP3 inflammasome in the pathogenesis of AP AP is an inflammatory disorder characterized by excessive activation of pancreatic enzymes due to diverse etiological factors, leading to autodigestion, edema, hemorrhage, and necrosis of pancreatic parenchyma and adjacent tissues

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As of April 22, 2026, it was removed from FDA Category 2, but the FDA's Pharmacy Compounding Advisory Committee will not consider it for the 503A bulks list until the July 23, 2026 meeting

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