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GPX1 and GPX 4 are glutathione-dependent, whereas the others are not (Deponte, 2013)

Real-world clinical experience with idebenone in the treatment of Leber hereditary optic neuropathy

13 This investigation demonstrated the benefits of the drug not only in lowering cardiovascular mortality but also in increasing overall survival rate of those diabetic patients who were obese 18 and has more recently been shown to reduce cardiovascular morbidity in individuals with non-alcoholic fatty liver disease