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A peer-reviewed overview in the International Journal of Molecular Sciences (Araj et al., Medical University of Warsaw, 2025) establishing Epithalon as a highly bioactive pineal tetrapeptide with documented mechanisms spanning telomere maintenance, epigenetic regulation, antioxidant defense, immune recalibration, and circadian rhythm restoration provides the scientific framework for all five mechanisms described in this section

Initial data processing included Fourier transformation, automated phasing, signal integrity checks, baseline correction, background noise removal, and spectral alignment

Because it is an ester of palmitic acid (C16), it falls into the range that the Malassezia yeast can feed on and is considered not fungal acne safe

Yet, the few trials to date are promising