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Beck and colleagues reported in 2014 that the 117-patient proof-of-concept study found ipamorelin well tolerated but did not reach statistical significance on its primary composite gastrointestinal endpoint at the studied dose

ACS Appl Mater Interfaces 12(40):4450844522 Lin S et al (2020) Antioxidative and angiogenesis-promoting effects of tetrahedral framework nucleic acids in diabetic wound healing with activation of the Akt/Nrf2/HO-1 pathway

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Cigarette smoke can reduce the expression of Frizzled receptor 4 (FZD4) in alveolar epithelial cells and enhance the phosphorylation of -catenin, inhibiting epithelial proliferation and alveolar repair mediated by the classic Wnt signalling pathway