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Siekmeier R, Scheuch G

When someone develops a deficiency, these symptoms usually appear slowly: Hair starts thinning and might fall out completely Red, scaly rash shows up around the eyes, nose, mouth, and perineum Nails become brittle Neurological issues appear including depression, lethargy, hallucinations, and tingling in extremities [18] Some groups have higher risks of deficiency: kidney dialysis patients, smokers, people with Crohn's disease, those on strict diets, and anyone taking certain antibiotics or anticonvulsants [19]

These skin reactions, known as Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), can be fatal

Kroeger-Koepke MB, Reuber MD, Iype PT et al (1983) The effect of substituents in the aromatic ring on carcinogenicity of N-nitrosomethylaniline in F344 rats