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Locating and enrolling the right population fast enough for a therapy to be effective were major hurdles, he explains

doi: 10.1016/j.hlc.2022.12.015 Foster, Victoria, Saez, Natalie, Gillespie, Ellen, Jogia, Trisha, Reid, Chantelle, Maljevic, Snezana, Jung, Woncheol, Lao, Hong W., Ruitenberg, Marc Jan and King, Glen (2023)

Clinical otolaryngology : official journal of ENT-UK

Chloramphenicol can bind to the active site of CYP3A4, inhibit its catalytic function, and then prolong drug half-life, leading to toxic accumulation (Park et al., 2003)