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Furthermore, esculetin (5 mg/kg) can inhibit the production of NO, TNF-, IL-6, iNOS and nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing in DSS-induced colitis rats by inhibiting the activation of the NF-B and MAPK signaling pathways (86,87)

Single-cell gel electrophoresis (Comet assay) For alkaline comet, lung tissue was homogenized in 1 ml of PBS (Ph 7.4), and clean glass slides were prepared by dipping in 1% normal melting point agarose

Erecinska, M., Nelson, D., Daikhin, Y

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