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Healthcare professionals are encouraged to report all suspected interactions and ADRs via the Yellow Card scheme, even if causality is uncertain

Cu/Zn-SOD is increased in the CL during the early to mid-luteal phase, but it is decreased during the regression phase, which could explain the increase in ROS concentrations during regression, and this change in activity is similar to that in progesterone concentrations

Inadequate CL function now stands recognized as a leading cause of serious pregnancy complications which also include preterm birth together with intrauterine growth restriction (IUGR) (186)