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Figure 3 Immune Cell Trafficking Across the BBB Transmigration of immune cells into the brain is crucial in pathologies with an inflammatory component, such as multiple sclerosis (MS)

NTR1 agonists can exert neuroprotective effects and improve cognitive function by alleviating excessive microglial activation and inhibiting oxidative stress, cell apoptosis, and synaptic loss in the hippocampus [67, 68]