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Additionally, SCFAs can modulate the levels of neurotransmitters and neurotrophic factors and regulate the expression of tryptophan 5-hydroxylase, the enzyme involved in the synthesis of serotonin, and tyrosine hydroxylase, the enzyme involved in the rate-limiting step in dopamine, noradrenaline, and adrenaline synthesis (18, 132, 164, 222)

If a doctor prescribes B12 injections, symptoms like fatigue, weakness, depression, and more may resolve within generally resolve in six to 12 weeks

Doctors sometimes attribute symptoms like tiredness, memory loss, and cognitive dysfunction to natural ageing, even in patients as young as their early fifties

Daily dosing at higher amounts may require additional supply for longer cycles