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We next explored whether the NRF2 system in SCLC is capable of responding to inhibition of KEAP1, the E3 ligase responsible for regulating NRF2 protein levels

Bai X, Gao M, Syed S, Zhuang J, Xu X, Zhang XQ

Purging: When you introduce an active like azelaic acid that affects cell turnover, a 'purging' phase can occur, where underlying microcomedones come to the surface