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This phenomenon presents a promising opportunity for designing drug delivery systems that specifically target tumors

Binding of the chaperone Jac1 protein and cysteine desulfurase Nfs1 to the ironsulfur cluster scaffold Isu protein is mutually exclusive

HIF bind to HIF-responsive elements (HRE) in the erythropoietin promoter, stimulating transcription (Souma et al 2015) and increasing erythropoietin production

We find that the binding site of both compounds is identical to that for a similar molecule that remains naturally attached to the virus 7 , and to the binding site observed for the benzene-sulfonamide derivative in complex with Coxsackievirus B3 8 , identifying the biological role for this binding site