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The user reported that their body began attacking its own joints, resulting in debilitating pain, an inability to walk or stand, and severe gastrointestinal cramping

It has decades of randomized controlled trial data behind it and is widely regarded as the reference-standard topical retinoid against which newer molecules are measured

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This is why ex vivo findings need to be confirmed in human trials which subsequent studies like the 2016 GHK peptide clinical trial and the 2021 copper tripeptide serum trial have done