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Liver-expressed antimicrobial peptide 2 (LEAP-2), the endogenous noncompetitive allosteric antagonist of the growth hormone secretagogue receptor 1a (GHSR1a), was recently identified as a key endocrine factor regulating systemic energy metabolism

In fact, the possibility of using glutathione for therapeutic purposes other than oxidative stress and further exploring the mechanisms by which it exerts its effects will also be helpful

The statistical distribution of the number of PSMs identified per peptide segment and the distribution of missed cleavage sites ( Figures 3B, C ) showed that a high proportion of peptide segments had zero missed cleavage sites (85.2%), meeting quality control requirements

doi: 10.1093/ageing/26.5.353 17