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doi: 10.1016/j.immuni.2018.03.007 14 WangYCWangXYuJMaFLiZZhouYet al

Evaluation of antioxidant and antigenotoxic activity of two flavonoids from Rhamnus alaternus L.(Rhamnaceae): Kaempferol 3-O--isorhamninoside and rhamnocitrin 3-O--isorhamninoside

The potential antidepressant effects of exogenous ALC in alleviating depressive-like behavior may be attributed to the modulation of NO and, consequently, the modulation of serotonin and other neurotransmitters, as well as attenuating oxidative/nitrosative stress, affecting NO production in the PFC