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Observations from various rodent studies indicate there were no visual signs of toxicity

Cyanocobalamin : Synthetic form, requires conversion to active B12, longer shelf life, lower cost Methylcobalamin : Bioactive form, immediate utilization, preferred for neurological symptoms, more expensive Hydroxocobalamin: Used for cyanide poisoning, longest-acting Standard dose: 1000mcg/ml Routes: Deep IM (gluteal/deltoid) or subQ (abdominal) Loading phase: Daily/weekly for 1-4 weeks Maintenance: Monthly or every 3 months (hydroxocobalamin) No need for aspiration before injection Oral absorption requires intrinsic factor (absent in pernicious anemia) and healthy ileum

This injury can be more severe because the injured nerves are pulled out of the spinal cord (an avulsion injury)

Community protocols and the 2013 Hsieh trial reference roughly 250-500 IU, two to three times weekly, run continuously alongside testosterone to keep the testes active