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Furthermore, several animal model studies have suggested that certain gut Clostridia species may alleviate hepatic inflammation by modulating bile acid metabolism through their influence on immune-related pathways, such as the Farnesoid X receptor (FXR)/Vascular adhesion protein-1 (VAP-1) and the 7-dehydroxylation reaction (222224)

References 1 New England Journal of Medicine (2023)Triple-Hormone-Receptor Agonist Retatrutide for Obesity (Phase 2 trial

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